TMS is a good alternative for patients who have difficulty tolerating the side effects associated with antidepressant medications. Since TMS is non-systemic (does not circulate through the bloodstream), it does not have side effects typically seen with antidepressant medications (ie. weight gain, sexual dysfunction, nausea, dry mouth, sedation, etc.) The procedure is well-tolerated with few side effects such as headache and mild scalp discomfort. TMS has been cleared by the U.S. Food and Drug Administration (FDA) for the treatment of patients with depression who have failed to achieve satisfactory improvement from prior antidepressant medication.